459,99 zł

Bayesian Designs For Phase I-ii Clinical Trials

Książki Obcojęzyczne>Angielskie>Medicine>Medicine: general issues>Medical equipment & techniques>Medical research>Clinical trialsKsi...

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Sklep: Gigant.pl

379,99 zł

The Cure Fraction In Cancer Clinical Trials

Książki Obcojęzyczne>Angielskie>Mathematics & science>Mathematics>Probability & statistics

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Sklep: Gigant.pl

379,99 zł

The Cure Fraction In Cancer Clinical Trials

Książki Obcojęzyczne>Angielskie>Mathematics & science>Mathematics>Probability & statistics

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Sklep: Gigant.pl

419,99 zł

Cancer Clinical Trials

Książki Obcojęzyczne>Angielskie>Medicine>Medicine: general issues>Medical equipment & techniques>Medical research>Clinical trialsKsi...

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Sklep: Gigant.pl

399,99 zł

Cancer Research And Clinical Trials In Developing Countries

Książki Obcojęzyczne>Angielskie>Medicine>Medicine: general issues>Medical equipment & techniques>Medical research>Clinical trialsKsi...

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Sklep: Gigant.pl

94,99 zł

A Handbook For Clinical Investigators Conducting Therapeutic Clinical Trials Supported By Ctep, Dctd, Nci

Książki Obcojęzyczne>Nieprzypisane

0x00bf4a9600000000

Sklep: Gigant.pl

319,99 zł

A Practical Guide To Designing Phase II Trials In Oncology

Książki Obcojęzyczne>Angielskie>Medicine>Medicine: general issues>Public health & preventive medicine>Epidemiology & medical statistics...

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Sklep: Gigant.pl

812,81 zł

Clinical Trials - A Methodologic Perspective 3e John Wiley & Sons Inc

Książki / Literatura obcojęzyczna

Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studiesThis Third Edition builds on the text's reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area.The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections.In addition, this book:Features accessible and broad coverage of statistical design methods--the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designsTeaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methodsContains an introduction and summary in each chapter to reinforce key pointsIncludes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledgeProvides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the bookClinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists.Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world's leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.

Sklep: Libristo.pl

336,66 zł

Prostate & Renal Cancer Benign Prostatic Hyperplasia Parthenon Publishing Group

Medycyna > English Division

This is the seventh monograph in the series Progress and Controversies in Oncologic Urology (PACIOU). Containing contributions from experts from around the globe, this book provides the most up-to-date information available on the mechanisms and treatment of prostate cancer and male sexual dysfunction. Highlighting the relationship between research results and the clinical practice, the discussions include the diagnosis and therapy of benign prostate cancer, diagnosis and outcomes in locally confined prostate cancer, epidemiology, risk factors, renal cancer, and the results of phase I and phase II trials of new drug treatments.

Sklep: Ksiazki-medyczne.eu

499,99 zł

Operative Standards For Cancer Surgery

Książki Obcojęzyczne>Angielskie>Medicine>Surgery>Surgical oncology

0x001b71f700000000

Sklep: Gigant.pl

190,65 zł

Pocket Guide to Bishosphonates in Clinical Practice Preventi Blackwell Science

Medycyna > English Division

The potential capacity of the biphosphonates to intervene in osseous remodeling was recognized more than 30 years ago. The biphosphonates inhibit osteoclastic activity. In spite of advances in early detection, surgey, chemo-and radiotherapy, metastatic bone disease is still a major and in many cases intractable clinical problem. The biphosphonates are now the most effective agents in the management of bone metastases - as shown by trials in patients with breast and prostate cancer, and in multiple myeloma. Bone pain, new ostelytic events and pathologic fractures are decreased and complications associated with these events are avoided. Existing osteolytic lesions may even be reversed. New fields of indications of biphosphonates are shown to be in the adjuvant therapy of breast cancer and in stage 1 multiple myeloma to prevent skeletal destruction and also to inhibit tumor growth. Over the past few years the biphosphonates have proved their value also in many other conditions such as Paget's disease of bone, osseous disorders with an osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic agents will be in these disorders, and particularly in so-called primary osteoporosis which evenually effects anyone who lives long enough, causing widespread morbidity with drastic economic consequences both individually and nationally. The authors' aim is to provide an office and desk companion - comprehensive, concise, practical for easy reference - an up-to-date guide for prevention and therapy of skeletal complications whenever and wherever they occur in general and specialized medical practice.

Sklep: Ksiazki-medyczne.eu

690,30 zł

Principles of Clinical Pharmacology Elsevier Books

Książki / Literatura obcojęzyczna

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science.§Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. Offers an expanded regulatory section that addresses US and international issues and guidelines. Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.§

Sklep: Libristo.pl

589,50 zł

Statins Martin Dunitz

Zdrowie, medycyna

Provides background information and describes the lipid world before the discovery of statinsPresents an up-to-date and in-depth review of statins from both a scientific and clinical viewpointExamines existing and emerging statins and their effectiveness in reducing serum cholesterolIncludes coverage of the effects of statins on non-vascular conditions such as osteoporosis, cancer, dementia, and diabetesContains new chapters covering combination therapy in lipid-lowering, new Megatrials, and the PROSPER study Building upon the foundation set in the first edition, Statins: The HMG-CoA Reductase Inhibitors in Perspective examines existing and emerging statins and their beneficial effectiveness in reducing serum cholesterol. The breadth of coverage and depth of information in this book provide an authoritative guide to statins from their discovery through the major clinical trials to the present and explores the future of statin trials and lipid-lowering therapy beyond statins.The book tells the story of statins, for the most part in the words of those who lived it. The major clinical trials from Scandinavia, North America, Australia, New Zealand, and Scotland are detailed by those who conducted them. The book includes information on the pharmacology and mechanisms of action, the statin angiographic trials, the use of statins after vascular surgery, guidelines for the use of the statins in clinical practice, and the cost-effectiveness of statin therapy. New chapters cover combination therapy in lipid-lowering, new 'Megatrials' (HPS and PPP), and the PROSPER study.

Sklep: Albertus.pl

563,27 zł

New Cytokines as Potential Drugs Springer Basel

Książki / Literatura obcojęzyczna

Over the past ten years, a number of cytokines and growth factors have §proven to be as effective therapeutics. While these products have §certainly established recombinant biologics as a major pharmaceutical §growth sector, the continued interest in this class of drugs arises from §the fact that today we have a far better understanding of the human §immune response, both at a cellular and molecular level. §This has resulted in a more methodical characterisation of these factors §which has given clinical researchers an opportunity to plan Phase 1 §clinical trials that can provide substantial information on the activity §of the cytokine in humans. Currently, a great deal of effort is also §being channelled into identifying cytokines from the various DNA §databases. §Our major objective for this book is to profile cytokines that have been §recently identified. The therapeutic potential of these cytokines based §on their known properties will be discussed by the authors. The main aim §of this book is to provide...

Sklep: Libristo.pl

496,62 zł

New Cytokines as Potential Drugs Birkhauser

Medycyna > English Division

Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics. While these products have certainly established recombinant biologics as a major pharmaceutical growth sector, the continued interest in this class of drugs arises from the fact that today we have a far better understanding of the human immune response, both at a cellular and molecular level. This has resulted in a more methodical characterisation of these factors which has given clinical researchers an opportunity to plan Phase 1 clinical trials that can provide substantial information on the activity of the cytokine in humans. Currently, a great deal of effort is also being channelled into identifying cytokines from the various DNA databases. Our major objective for this book is to profile cytokines that have been recently identified. The therapeutic potential of these cytokines based on their known properties will be discussed by the authors. The main aim of this book is to provide...

Sklep: Ksiazki-medyczne.eu

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t1=0.03, t2=0, t3=0, t4=0.016, t=0.03