krainaksiazek local drug delivery system in periodontics 20045557

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Peridontal Drug Delivery: Ushering New Era in NDDS - 2834695229

310,91 zł

Peridontal Drug Delivery: Ushering New Era in NDDS LAP Lambert Academic Publishing

Książki / Literatura obcojęzyczna

Endosseous dental implants have revolutionized the fields of implants and periodontics. During the last decade, a great deal of information has been generatedconcerning the effectiveness and predictability of endosseous implants. Implant placement is a viable option in the treatment of partial and full edentulism and has become an integral facet of periodontal therapy. The available implants are remarkably successful. However, there is no one ideal implant system. The following areas need further study: edentulous sites with inadequate bone for endosseous implants, splinting of implants to natural teeth, long-term effects of microbial and occlusal stresses, the prevention and treatment of peri-implant infection and disease, effects of implants on alveolar ridge maintenance, and routine maintenance protocols. Research on implant design for narrow ridges and atrophic jaws is ongoing, and the clinical efficacy of localized ridge augmentation and sinus floor grafts is being investigated. An area of research with future clinical significance is the use of growth factors and osteoinductive substances which may be applied locally or incorporated into the implant s surface.


Gastric Floating Microcapsules of Metformin HCl - 2834695276

345,66 zł

Gastric Floating Microcapsules of Metformin HCl LAP Lambert Academic Publishing

Książki / Literatura obcojęzyczna

Despite tremendous advancement in the drug delivery, oral route remains the preferred route for drug administration because of low cost therapy and ease of administration leads to higher levels of patient compliance. Metformin HCl, which is an antihyperglycaemic agent widely, used in the management of NIDDM, gives low bioavailability problem due to its site absorption limitations. Although, metformin extended release tablet formulations were well established, but it causes a great fluctuations in plasma drug levels and fail to improve the bioavailability. But microcapsule formulation offer several advantages over other sustained release systems, especially matrix type tablets; as they can be widely distributed throughout the GI tract and produce local high concentration of drug at the absorption site. Henceforth, the designing of floating microcapsules would be a suitable delivery system for metformin with a new choice of an economical, safe and more bioavailable formulation in the management of NIDDM. This book represents a unique attempt to overview the full range of approaches to the design of a dosage form for gastric retention of drug with absorption limitation problems.


Sklepy zlokalizowane w miastach: Warszawa, Kraków, Łódź, Wrocław, Poznań, Gdańsk, Szczecin, Bydgoszcz, Lublin, Katowice

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