krainaksiazek nf b related genetic diseases 20123785

- znaleziono 2 produkty w 1 sklepie

NF-kB-Related Genetic Diseases - 2834152938

258,04 zł

NF-kB-Related Genetic Diseases Springer, Berlin

Książki / Literatura obcojęzyczna

This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.§


Mechanistic Studies of Drug-Disease and Drug-Drug Interactions - 2834694643

399,08 zł

Mechanistic Studies of Drug-Disease and Drug-Drug Interactions VDM Verlag Dr. Müller

Książki / Literatura obcojęzyczna

Every minute, we are exposed to and involuntarily absorb xenobiotics which may produce beneficial outcomes or harmful effects on our bodies. Drug metabolism is initially a defensive mechanism driven by certain enzymes to facilitate excretion and in turn reduce the body burden of the absorbed xenobiotics. However, the capacity of this protective system is regulated by factors including disease states, absorbed xenobiotics and genetic factors. Cytochrome P450 3A4 (CYP3A4) is the most abundant phase I drug metabolism enzyme in human liver and its expression levels affect the capacity of drug metabolism. In this book, mechanisms have been investigated on regulation of CYP3A4 gene expression through modulating pregnane X receptor transcriptional activity under inflammation and by xenobiotics. This book also introduces basic knowledge of xenobiotics and their disposition, drug metabolizing systems, nuclear receptors as xenosensors, as well as inflammation and NF- B. The information provided is useful to professionals and students in the fields of pharmaceuticals, pharmacy, medicinal therapeutics, chemical risk assessment and related scientific research.


Sklepy zlokalizowane w miastach: Warszawa, Kraków, Łódź, Wrocław, Poznań, Gdańsk, Szczecin, Bydgoszcz, Lublin, Katowice

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