637,24 zł

Textbook of Personalized Medicine Springer

Książki / Literatura obcojęzyczna

This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.

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310,52 zł

Urbanization, Biodiversity and Ecosystem Services: Challenges and Opportunities Springer

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The book will be based on scientific analyses and assessments conditions and trends of urbanization, urban ecosystem services, scenarios, typologies of urbanization, governance challenges, and analyses of urban landscapes as social-ecological systems. It will review and synthesize existing information, as well as present new original analyses and data. It will consist of 5 sections and 14 15 chapters, in total 300 400 pages.§The aim of this assessment is to: Serve as the first comprehensive global analysis of how urbanization and urban growth impact biodiversity and ecosystem dynamics in terrestrial, freshwater, and marine systems. Provide an overview, analysis, and response to knowledge gaps in our understanding of urbanization processes and urban social-ecological systems. Address how urban biodiversity and ecosystems could be used, restored, and created in innovative ways to reduce vulnerability and enhance resilience, and how cities could move from being just consumers to also generate ecosystem services and reduce footprints (redefining the function of cities).

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563,27 zł

Solitons in Molecular Systems Springer

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Approach your problems from the It isn't that they can't see the end and begin with the answers. solution. It is that they can't Then one day, perhaps you will see the problem. find the final question. G.K. Chesterton. The Scandal of 'The Hermit Clad in Crane Father Brown 'The Point of a Pin'. Feathers' in R. van Gulik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of mono graphs and textbooks on increasingly topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, coding theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical pro gramming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electric engineering can use Stein spaces. And in addition to this there are such new emerging subdisciplines as "complete integrable systems", "chaos, synergetics and large-scale order", which are almost impossible to fit into the existing classifica tion schemes. The draw upon widely different sections of mathematics.

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563,27 zł

Problems of Coordination in Economic Activity Springer

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Coordination is extremely important in economic, political, and social life. The concept of economic equilibrium is based on the coordination of producers and consumers in buying and selling. This book reviews the topic of coordination from an economic, theoretical standpoint. The aim of this volume is twofold: first, the book contributes to the ongoing research on the economics of coordination; and second, it disseminates results and encourages interest in the topic. The volume contains original research on coordination including general game-theoretic questions, particular coordination issues within specific fields of economics (i.e. industrial organization, international trade, and macroeconomics), and experimental research.§

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563,27 zł

Bioinformatics: An Introduction Springer

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An Introduction to Bioinformatics is intended to be a complete study companion for the advanced undergraduate or beginning graduate student. It is self-contained in the sense that whatever the starting point may be, the reader will gain insight into bioinformatics. Underlying the work is the belief that bioinformatics is a kind of metaphoric lens through which the entire field of biology can be brought into focus, admittedly as yet imperfect, and understood in a unified way. Reflecting the highly incomplete present state of the field, emphasis is placed on the underlying fundamentals and acquisitions of a broad and comprehensive grasp of the field as a whole. §Bioinformatics is interpreted as the application of information science to biology, in which it plays a fundamental and all-pervasive role. This interpretation enables a remarkably unified view of the entire field of biology to be taken and hence offers an excellent entry point into the life sciences for those for whom biology is unfamiliar. §

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563,27 zł

Motion and Knowledge in the Changing Early Modern World Springer

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This volume comprises studies of the early modern drama of motion and transformation of knowledge. It is unique in taking its global nature as fundamental and contains studies of the theme of motion and knowledge in China, Europe and the Pacific from the 16th to the 18th century.§People living around the turn of the 17 th century were experiencing motion in ways beyond the grasp of anyone less than a century earlier. Goods and people were crossing lands and oceans to distances never envisioned and in scales hardly imaginable by their recent predecessors. The earth itself has been set in motion and the heavens were populated by a whole new array of moving objects: comets, moons, sun spots. Even the motion of terrestrial objects so close at hand and seemingly obvious was being thoroughly reshaped. In the two centuries to follow, this incessant, world-changing motion would transform the creation, interpretation and dissemination of knowledge and the life and experiences of the people producing it: savants, artisans, pilots, collectors. §

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310,52 zł

Arent de Gelder Springer

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Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

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866,57 zł

Developments in Foundation Law in Europe Springer

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This book deals with foundation law in various European countries. It sums up contributions from the most outstanding experts in foundation law in fourteen countries. These are either civil law or common law, and their socio-economical situation is considerably different.§Despite the outstanding differences in each country, foundations have been growing in number and importance all over Europe in the last decades. Political, economical and social changes occurred in various European countries increased foundations' role. The need to focus on foundations' laws and regulations arose in many States for different reasons.§The contributions in this book focus in particular on the recent development of foundation law, on the evolution foundations have undergone in recent years and on trends in law.§

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259,97 zł

Die Relativitat Von "Welt" Springer

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Das Werk zeigt, inwiefern ein naives Verständnis von "Welt" der Komplexität moderner Wissenschaften nicht gerecht wird. Es liefert einen wissenschaftstheoretischen Rahmen, in dem die interdisziplinären Fragestellungen von Psychologie, Neurowissenschaften, Biologie und Quantenphysik verstanden werden können, ohne in Aporien zu führen. Auf diese Weise trägt der Autor dazu bei, dass Grundlagenprobleme wie der Zusammenhang von Körper und Geist, Gehirn und Bewusstsein oder die Lokalisierung physikalischer Objekte in Raum und Zeit angemessen verstanden werden können. Entscheidend ist dabei der jeweilige Bezugsrahmen, der zu beachten ist: Epistemisch verschiedene Welten (Epistemological Different Worlds, abgekürzt EDW's) helfen, hypertrophe Begriffe (Scheinwelten) einer "realen Welt" ab- bzw. in die jeweiligen Schranken zu verweisen.

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374,84 zł

Quantum Mechanics for Pedestrians 1 Springer

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This book provides an introduction into the fundamentals of non-relativistic quantum mechanics. The first part of a two-volume reference, it develops essential principles and supports learning with exercises and problems with solutions.

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629,20 zł

Polynomials Springer

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The book extends the high school curriculum and provides a backdrop for later study in calculus, modern algebra, numerical analysis, and complex variable theory. Exercises introduce many techniques and topics in the theory of equations, such as evolution and factorization of polynomials, solution of equations, interpolation, approximation, and congruences. The theory is not treated formally, but rather illustrated through examples. Over 300 problems drawn from journals, contests, and examinations test understanding, ingenuity, and skill. Each chapter ends with a list of hints; there are answers to many of the exercises and solutions to all of the problems. In addition, 69 "explorations" invite the reader to investigate research problems and related topics.

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1675,47 zł

Diatom World Springer

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Diatom biology, genomics and ecology are becoming more relevant to the human species. While there have been recent compilations of some of the applied aspects of diatoms, and the dizzying pace of taxonomic revisions, this new volume bring us up to date on their classification, biology and ecology, as well as covering the topics of genomics and applied uses. In this collection, some of the leaders in diatom research present either new information or summarize recent research efforts on a wide range of topics, including the tree of life of diatoms, their classifications, the wide habitats and ecological spectra the group exploits, as well as the beauty of their form. This volume celebrates the diversity, emerging areas of research and fascinating ecology of the diatoms bringing this group of world-renown and emerging research leaders together. 'The Diatom World' will foster greater appreciation and research contributions on this incredibly diverse and fascinating group of organisms.

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866,57 zł

Algorithms for Computer Algebra Springer

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Algorithms for Computer Algebra is the first comprehensive textbook to be published on the topic of computational symbolic mathematics. The book first develops the foundational material from modern algebra that is required for subsequent topics. It then presents a thorough development of modern computational algorithms for such problems as multivariate polynomial arithmetic and greatest common divisor calculations, factorization of multivariate polynomials, symbolic solution of linear and polynomial systems of equations, and analytic integration of elementary functions. Numerous examples are integrated into the text as an aid to understanding the mathematical development. The algorithms developed for each topic are presented in a Pascal-like computer language. An extensive set of exercises is presented at the end of each chapter. Algorithms for Computer Algebra is suitable for use as a textbook for a course on algebraic algorithms at the third-year, fourth-year, or graduate level. Although the mathematical development uses concepts from modern algebra, the book is self-contained in the sense that a one-term undergraduate course introducing students to rings and fields is the only prerequisite assumed. The book also serves well as a supplementary textbook for a traditional modern algebra course, by presenting concrete applications to motivate the understanding of the theory of rings and fields.

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563,27 zł

Rare Diseases Springer

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This book focuses on predictive, preventative and personalized medicine (PPPM) and how it is related to the healthcare of rare diseases. Readers will discover how advanced rare diseases healthcare provides an excellent proof-of-principles for the personalisation of healthcare systems on a global scale. Chapters look at national plans for rare disease, at biobanking, gene identification, rare cancers, virus gene therapy , induced pluripotency for cell therapy amongst other topics. There is a chapter dedicated to personalized medicine for hereditary deafness and another exploring the complexity of genotype-phenotype correlations. Specific diseases such as Fabry's, Gauchers and mitochondrial cytopathies are highlighted and we look at enzyme replacement therapy in lysosomal storage diseases. This work is part of a series, produced with the involvement of the European Association for Predictive, Preventive and Personalised Medicine. The series focusses on the concept of an integrative medical approach by PPPM. This volume is dedicated to all aspects related to the prediction, prevention and personalised treatments of rare diseases, and in doing so it explores developments relevant to all medical branches. The authors cover ethical considerations, the creation of a robust platform for professional communication, synergies with patient organisations, doctor-patient collaboration and a new philosophy of integrative medicine by PPPM. This volume serves as a reference source for scientific and medical centres in the field and can be used both at medical curricula and graduate level in the life sciences. Those who place a special emphasis on healthcare promotion and innovations intended to combat rare diseases, save the affected lives and enhance life quality will all find this book of great value.

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246,31 zł

Boston Studies in the Philosophy of Science Springer

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Proceedings of the Boston Colloquium for the Philosophy of Science 1966/1968

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